Where to Look
First focus on the street: In the first column, pay special attention to the street (written out so that they span multiple rows). Skip the rows that do not belong to the street you are looking for.
House number: When you have found the street of interest, focus on the house number in the second column. The census taker likely visited the houses out of order so expect the number to jump around.
Address fields in a 1950 US Census Population Schedule for Hoboken, New Jersey. Enumeration District 27-66, Sheet 80.